Endocrine Abstracts

Primary therapy in prolactinomas, the most frequent pituitary adenomas, consists in ergot derivatives dopamine agonists (bromocriptine or cabergoline) which lowers prolactin levels and shrink the tumour. Bromocriptine was the first drug used, but the therapeutic levels are attained after several days/weeks, therefore an acute suppression test is not possible. However, the biological response is variable and 10% of prolactinomas are resistant to medical therapy. In order to eva...

Short stature is a frequent finding among patients with beta-thalassemia major, with a major impact on the quality of life and a multifactorial aetiology.Aim: To study the relationship between growth retardation of thalassemic patients and associated sistemic conditions and endocrine complications.Subjects and methods: Cross-sectional study on 59 patients with βthalassemia major who did not reach their final height, with a mea...